Promotes Complete Digestion of Dairy Proteins

ProteaseCW is a proprietary blend of acid-resistant, non-animal derived digestive enzymes uniquely formulated to provide substantial proteolytic activity aimed at breaking down the hard-to-digest casein and whey proteins found in dairy foods and protein supplements, helping to enhance its nutritional value and relieve the gastrointestinal discomfort associated with dairy intolerance.*

The Problem

Dairy foods and many protein supplements contain casein and/or whey, proteins the body has difficulty digesting that often results in not only a significant loss in nutritional value but also gastrointestinal discomfort and, in some cases, serious immune responses.

The Solution

ProteaseCWis precisely-formulated to assist the body’s own digestive enzymes in thoroughly breaking down dairy protein (casein and whey), releasing essential amino acids and beneficial bioactive peptides as well as minimizing intolerance to dairy protein.* Avoiding dairy foods altogether may seem like an easy solution to the problem. However, casein and/or whey are often used for nutritional or processing purposes in other common foods, medications and dietary supplements and may not be clearly identified on the label.[1,6]

How ProteaseCW™ Works

A complex blend of both endopeptidases and exopeptidases, ProteaseCW helps maximize the digestion of casein and whey proteins found in dairy foods and many high protein supplements.* Casein contains amino acid sequences that are unusually high in the amino acid, proline.[7] These proline-dense regions exhibit structural features that cause folding and helical cross-linking of the protein preventing efficient hydrolysis by the body’s gastric, pancreatic and intestinal brush border proteases.[8,9] The peptidases found in ProteaseCW exhibit substantial DPP-IV activity capable of hydrolyzing the difficult proline bonds in casein.[10] The other major dairy protein, whey, primarily contains beta-lactoglobulins and alpha-lactalbumins which are resistant to hydrolysis by gastric pepsin.[11,12] Their compact globular structure and numerous disulfide bonds hinders easy access to the protein sites specific to pepsin action.[2,13,14] The unique blend of proteases in ProteaseCW exhibits a wide range of bond specificity at various pH levels so it is capable of optimal effectiveness in the acidic conditions of the stomach. These proteases begin their digestive action immediately upon arriving in the stomach, continuing to hydrolyze whey and casein before it reaches the intestinal mucosa where it can stimulate an inflammatory immune response.[5,15,16]

Why ProteaseCW™

ProteaseCWis exceptionally effective at breaking down casein and whey, providing the body with more nutrition from dairy foods and protein supplements while lowering the risk of dairy protein intolerance.* The powerful combination of highly purified enzymes found in ProteaseCWare concentrated from the fermentation of non-genetically modified microorganisms, primarily Aspergillus species with a long history of safe use.  This unique blend provides the right proportions of acid-stable, neutral and alkaline proteases and peptidases specifically chosen for their combined ability to efficiently cleave dairy protein at multiple bond locations yielding smaller peptides and single amino acids.

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  12. Nakano T, Simatani M, Murakami Y, Sato N, Idota T. Digestibility and Absorption of Enzymatically Hydrolyzed Whey Protein. Nippon Eiyo Shokuryo Gakkaishi. 1994; 47 (3): 195-201.
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